Journal: Journal of Genetic Engineering & Biotechnology

Article Title: Potential role of Adansonia digitata nanoparticles on colorectal cancer induced by colorectal cancer cells (SW620) in nude mice

doi: 10.1016/j.jgeb.2026.100659

Figure Lengend Snippet: Oxidative stress markers in nude mice colon treated with SW620, AD, ADNPs1, and ADNPs2. A significant change at p < 0.05 in MDA and a non-significant change at p > 0.05 in SOD and catalase activity. Values presented as mean ± S.E., a, b different superscripts within columns are significantly different ( P < 0.05).

Article Snippet: The SW620 human colorectal cancer cell line was obtained from the American Type Culture Collection (ATCC, Rockville, MD, USA).

Techniques: Activity Assay

Journal: Journal of Genetic Engineering & Biotechnology

Article Title: Potential role of Adansonia digitata nanoparticles on colorectal cancer induced by colorectal cancer cells (SW620) in nude mice

doi: 10.1016/j.jgeb.2026.100659

Figure Lengend Snippet: Anti-apoptotic/pro-apoptotic protein level markers in nude mice colon treated with SW620, AD, ADNPs1, and ADNPs2. A significant change at p < 0.05 compared to the SW620 group in cytochrome c and a non-significant change at p > 0.05 in caspase3, BAX, and BCL-2. Values presented as mean ± S.E., a, b different superscripts within columns are significantly different ( P < 0.05).

Article Snippet: The SW620 human colorectal cancer cell line was obtained from the American Type Culture Collection (ATCC, Rockville, MD, USA).

Techniques:

Journal: Journal of Genetic Engineering & Biotechnology

Article Title: Potential role of Adansonia digitata nanoparticles on colorectal cancer induced by colorectal cancer cells (SW620) in nude mice

doi: 10.1016/j.jgeb.2026.100659

Figure Lengend Snippet: TGF-β, TNF-α, INOS, and IL-1β mRNA expression in nude mice colon treated with SW620, AD, ADNPs1, and ADNPs2. A significant change at p < 0.05 compared to the SW620 group in TGF-β, and a non-significant change at p > 0.05 in TNF-α, IL-1β, and INOS. Values presented as mean ± S.E., a, b, c different superscripts within columns are significantly different ( P < 0.05).

Article Snippet: The SW620 human colorectal cancer cell line was obtained from the American Type Culture Collection (ATCC, Rockville, MD, USA).

Techniques: Expressing

Journal: Cancer Discovery

Article Title: Negative Selection Maintains Grossly Altered but Broadly Stable Karyotypes in Metastatic Colorectal Cancer

doi: 10.1158/2159-8290.CD-24-0813

Figure Lengend Snippet: Ongoing copy number alterations in model systems. A, Schematic of the method used to obtain and sequence single cells from cultured colorectal cancer cell line SW620 and patient-derived organoid (PDO) 3994-1117. Cell line SW620 underwent single-cell dispensing using the cellenONE system, followed by direct library prep (DLP) while the 10× Genomics Chromium was used to prepare single-cell libraries from the patient-derived organoid 3994-1117. B, Heatmap showing CNAs in single cells from colorectal cancer cell line SW620 and ( C ) from patient-derived organoid 3994-1117. Red = gain, blue = loss. D, Phylogenetic tree constructed using CNAs in the colorectal cancer cell line SW620. E, Frequency of copy number gains and losses at the tips of the SW620 phylogenetic tree. F, Phylogenetic tree constructed using CNAs in the colorectal cancer organoid 3994-117. G, Frequency of copy number gains and losses at the tips of the 3994-117 phylogenetic tree (as in E ).

Article Snippet: The colorectal cancer cell line SW620 was obtained from the ATCC (CCL-227) and cultured in high-glucose DMEM with 10% FBS and 2% penicillin–streptomycin.

Techniques: Sequencing, Cell Culture, Derivative Assay, Single Cell, Cellenone, Construct